Signs of Edema include: ankle & leg swelling, changes in skin pigmentation, pain and discomfort particularly in the calf and/or ankle. Swelling and leg edema can be caused by an abnormal buildup of fluid in the soft tissues of the leg. Edema is multifactorial and can be caused by lymphatic dysfunction and/or a more progressive stage of venous reflux disease. Increased venous hypertension forces … Continue reading Ankle & Leg Swelling (Edema)